abstract：:Platelets are known to become activated during storage, but it is unclear whether such activation affects recovery or survival after platelet concentrate (PC) transfusion. With the use of flow cytometry to determine the percentage of platelets expressing the alpha-granule membrane protein 140 (GMP-140), a known adhesi...

journal_title：Transfusion

authors： Rinder HM,Murphy M,Mitchell JG,Stocks J,Ault KA,Hillman RS

更新日期：1991-06-01 00:00:00

abstract：:Blood Centers of California, Inc. (BCC) is a consortium of 19 independent blood centers that collectively draw approximately 800,000 units of whole blood each year. Over the past several years, a committee of BCC, composed primarily of medical and nursing directors at member institutions, developed a Uniform Donor Med...

journal_title：Transfusion

authors： Kolins J,Silvergleid AJ

更新日期：1991-05-01 00:00:00

abstract：:The immediate-spin (IS) crossmatch is a method that detects ABO incompatibility. However, under certain circumstances, this test may show unwanted negative or weak results, even though the red cells (RBCs) and serum being tested are ABO incompatible with each other. The present study investigated the potential effect ...

journal_title：Transfusion

authors： Shulman IA,Calderón C

更新日期：1991-03-01 00:00:00

abstract：:Two monoclonal antibodies (MoAbs), BRIC 66 (IgM) and BRIC 111 (IgG1), were produced by immunizing mice with ovarian cyst blood group A1 glycoprotein and Tn red cells (RBCs), respectively. Their specificities were determined by inhibitions using Tn sialoglycoproteins (SGPs), mucins (armadillo [ASG] and ovine [OSG] subm...

journal_title：Transfusion

authors： King MJ,Parsons SF,Wu AM,Jones N

更新日期：1991-02-01 00:00:00

abstract：:Autologous blood donors (ABDs) have been reported to have favorable attitudes toward returning as homologous blood donors (HBDs), but the frequency of return has not been well documented. ABDs eligible by history to be HBDs were followed at one blood center: 255 donating for elective surgery and 234 donating during pr...

journal_title：Transfusion

authors： McVay PA,Fung HC,Toy PT

更新日期：1991-02-01 00:00:00

abstract：:The transfusion of red cells (RBCs) was analyzed over a 4-year period (1984-1987), during which 9596 cesarean deliveries were performed. A total of 336 patients were identified as receiving RBC transfusions during or after cesarean delivery; 747 units of RBCs were administered. The overall incidence of transfusion in ...

journal_title：Transfusion

authors： Camann WR,Datta S

更新日期：1991-01-01 00:00:00

abstract：:The use of the direct manual hexadimethrine bromide (Polybrene) test (DPT) in the investigation of patients for autoimmune hemolytic anemia (AIHA) was evaluated. Seventy-nine blood samples from 68 patients were tested. A direct antiglobulin test (DAT) using monospecific reagents and the DPT were performed, and a conce...

journal_title：Transfusion

authors： Owen I,Hows J

更新日期：1990-11-01 00:00:00

abstract：:The in vivo viability and functional integrity of filtered platelets were compared with those of nonfiltered platelets in a controlled study. On two occasions, after template bleeding time, 14 healthy volunteers underwent plateletpheresis and received 600 mg of aspirin. Autologous 111In-labeled platelets were transfus...

journal_title：Transfusion

authors： Brecher ME,Pineda AA,Zylstra-Halling VW,Chowdhury S,Forstrom LA

更新日期：1990-10-01 00:00:00

abstract：:Most patients who need peripheral blood stem cell transplantation do not have peripheral venous access that would allow apheresis for stem cell collection. Subclavian apheresis catheters have an unacceptably high incidence of thrombosis-related access failure. A technique has been developed for translumbar placement o...

journal_title：Transfusion

authors： Haire WD,Lieberman RP,Lund GB,Wieczorek BM,Armitage JO,Kessinger A

更新日期：1990-07-01 00:00:00

abstract：:In Taiwan, the prevalence of circulating anti-HCV is 2 percent among first-time voluntary Chinese blood donors, 10 percent among donors with elevated ALT levels (greater than 45 IU/L), and higher among older men. The carrier rate for HBsAg was 18.6 percent and the frequency of positive HBV marker(s) (HBsAg, anti-HBc, ...

journal_title：Transfusion

authors： Lin-Chu M,Tsai SJ,Watanabe J,Nishioka K

更新日期：1990-06-01 00:00:00

abstract：:A number of different methods exist that use chromium-51 to determine platelet survival and recovery. A 1986 article in TRANSFUSION described the recommended methods for conducting such studies in the hope of standardizing methodology and permitting interlaboratory comparison of results. The results obtained with the ...

journal_title：Transfusion

authors： Rock G,Tittley P

更新日期：1990-06-01 00:00:00

abstract：:Bone marrow was harvested for the purpose of autologous bone marrow transplantation (ABMT) in 21 patients previously treated with chemotherapy and in complete remission from acute leukemia or non-Hodgkin's lymphoma. The volume required to obtain 2 x 10(8) nucleated cells per kg was less than 15 mL per kg in 13 patient...

journal_title：Transfusion

authors： Sonneveld P,de Leeuw CA,Schipperus M,Lindemans J,Abels J

更新日期：1990-05-01 00:00:00

abstract：:An example is presented of an IgG1, anti-Lu6, that reacted by indirect antiglobulin test and was capable of destroying antigen-positive red cells in vivo. Two methods for the measurement of red cell survival, 51Cr labeling and flow cytometry, gave the same result: 20 percent of the test dose of Lu:6 red cells was dest...

journal_title：Transfusion

authors： Issitt PD,Valinsky JE,Marsh WL,DiNapoli J,Gutgsell NS

更新日期：1990-03-01 00:00:00

abstract：:Flow cytometric analysis was performed on red cells (RBCs) to compare the antigen activity of various Rh phenotypes, including the rare variants Del and Du (both high-grade and low-grade), whose genotypes were confirmed or presumed by the family study. This appears to be the first report that the Del phenotype is due ...

journal_title：Transfusion

authors： Hasekura H,Ota M,Ito S,Hasegawa Y,Ichinose A,Fukushima H,Ogata H

更新日期：1990-03-01 00:00:00

abstract：:The ability to store platelets beyond 24 hours requires a functionally closed system. This study tested the ability of a cell separator bowl seal system to resist penetration of microbial contamination under normal running conditions and under extreme environmental stress. Three test organisms, Micrococcus luteus, Ser...

journal_title：Transfusion

authors： Jacobson MS,Kevy SV,Thorne GM,Goldmann DA,Blasetti L,Smith JW,Schaefer H

更新日期：1990-02-01 00:00:00

abstract：:In the procedure for quality control of red cell concentrates, made white cell (WBC)-poor by filtration, the particle-counting technique was found to be insufficiently sensitive in detecting the remaining WBCs and platelets. Therefore, direct radioimmunoassays were developed using murine monoclonal antibodies specific...

journal_title：Transfusion

authors： Webster MR,Prins HK,Huisman JG

更新日期：1990-02-01 00:00:00

abstract：:HLA and granulocyte-specific antibodies have been implicated in the production of transfusion-related acute lung injury (TRALI). Reported here is a case that suggests that the patient's preexisting condition may play an important role in determining whether TRALI develops upon transfusion of blood products containing ...

journal_title：Transfusion

authors： Van Buren NL,Stroncek DF,Clay ME,McCullough J,Dalmasso AP

更新日期：1990-01-01 00:00:00

abstract：:An antibody found in the serum of a Japanese blood donor detects a new high-frequency red cell antigen named UMC. UMC is absent from Inab phenotype cells, weakly expressed on Dr(a-) cells, and destroyed by alpha-chymotrypsin but not trypsin treatment of red cells. UMC is, therefore, a Cromer-related antigen. Immunoblo...

journal_title：Transfusion

authors： Daniels GL,Okubo Y,Yamaguchi H,Seno T,Ikuta M

更新日期：1989-11-01 00:00:00

abstract：:The number of cases of transfusion-associated acquired immune deficiency syndrome (TA-AIDS) that will be seen over the next few years is difficult to estimate, because of the uncertainty about the number of persons infected with the human immunodeficiency virus (HIV) via blood transfusion and about the duration of the...

journal_title：Transfusion

authors： Kalbfleisch JD,Lawless JF

更新日期：1989-10-01 00:00:00

abstract：:Th activation of red cells is characterized by agglutination with the peanut lectin from Arachis hypogaea and is diminished by treatment with proteolytic enzymes. The first cases of Th activation were associated with bacterial infections. More recently, a high incidence of Th activation in congenital hypoplastic anemi...

journal_title：Transfusion

authors： Wahl CM,Herman JH,Shirey RS,Kickler TS,Ness PM

更新日期：1989-09-01 00:00:00

abstract：:Fatal postoperative erythroderma (POE) developed in a 52-year-old woman with gallstones who underwent elective cholecystectomy. During surgery, she was transfused with 3 units of unirradiated packed red cells stored in the liquid state for at least 4 days after collection. The POE is believed to have been the result o...

journal_title：Transfusion

authors： Otsuka S,Kunieda K,Hirose M,Takeuchi H,Mizutani Y,Nagaya M,Sato G,Kasuya S,Matsutomo K,Noma A

更新日期：1989-07-01 00:00:00

abstract：:A new blood pack system for the preparation of white cell-depleted red cells was studied. The system is a modified additive-solution quadruple-unit blood pack that incorporates a cellulose-acetate fiber depth filter in-line between the AS-3 additive bag and the CP2D collection bag. Mean +/- SD white cell removal from ...

journal_title：Transfusion

authors： Davey RJ,Carmen RA,Simon TL,Nelson EJ,Leng BS,Chong C,Garcez RB,Sohmer PR

更新日期：1989-07-01 00:00:00

abstract：:Removal of white cells (WBCs) from platelets may reduce alloimmunization to WBC antigens, prevent febrile reactions, and improve platelet increments in multiply transfused patients receiving HLA-matched platelets. A new surface-modified fibrous polyester filter was evaluated; it requires no special processing of poole...

journal_title：Transfusion

authors： Kickler TS,Bell W,Drew H,Pall D

更新日期：1989-06-01 00:00:00

abstract：:Red cells (RBCs) prepared by a new system using centrifugation to produce neocyte enrichment were studied in two laboratories. The system used a blood bag with a geometric configuration such that younger, less dense cells could be separated from older, denser cells. Phthalate ester density gradient curves determined t...

journal_title：Transfusion

authors： Simon TL,Sohmer P,Nelson EJ

更新日期：1989-03-01 00:00:00

abstract：:The Platelet Monitoring System (PMS) and the Non-invasive Assessment of Platelet Shape and Concentration (NAPSAC) instruments which relate light scattering characteristics of platelet concentrates (PC) to platelet concentration and shape, were evaluated to determine their accuracy in assessing platelet quality during ...

journal_title：Transfusion

authors： George V,Holme S,Moroff G

更新日期：1989-03-01 00:00:00

abstract：:Vancomycin, an antibiotic similar in structure to ristocetin, is used to treat staphylococcal infections. However, vancomycin-induced hemagglutination complicated red cell (RBC) serologic testing in the blood bank. At concentrations greater than 3.0 mg per ml, vancomycin caused spontaneous macroscopic red cell (RBC) a...

journal_title：Transfusion

authors： Williams L,Domen RE

更新日期：1989-01-01 00:00:00

abstract：:Current standards for the preparation of factor VIII (FVIII) concentrates from human plasma recommend separation of plasma from red cells (RBCs) within 6 hours of blood donation, thereby reducing the volume of plasma from donated whole blood available for processing to FVIII concentrate. The decay of FVIII clotting ac...

journal_title：Transfusion

authors： Hughes C,Thomas KB,Schiff P,Herrington RW,Polacsek EE,McGrath KM

更新日期：1988-11-01 00:00:00

abstract：:The purpose of this study was to ascertain the cause for seasonal variations of donor deferral. Deferred donors and monthly temperatures from 1981 to 1984 were tallied and analyzed. Temperatures were categorized at 10-degree intervals from 15 degrees F to 75 degrees F. Donors failing the hemoglobin screening then unde...

journal_title：Transfusion

authors： Lau P,Hansen M,Sererat M

更新日期：1988-11-01 00:00:00

abstract：:We have estimated the risk of transmitting HIV infection from a unit of HIV seronegative blood collected in Los Angeles and Orange Counties, CA from March 1985 through February 1987. Our method consisted of lookback investigations and anti-HIV testing of living recipients of HIV seronegative units donated by persons w...

journal_title：Transfusion

authors： Kleinman S,Secord K

更新日期：1988-09-01 00:00:00

abstract：:The In(Lu) gene, which inhibits the expression of Lutheran blood group antigens by red cells (RBCs), also down-regulates the expression of an 80-kD glycoprotein, In(Lu)-related p80, by both RBCs and a subset of white cells. This study examined the expression of multiple-RBC p80 epitopes by autosomal and X-linked reces...

journal_title：Transfusion

authors： Telen MJ,Green AM

更新日期：1988-09-01 00:00:00

abstract：:Female blood donors with low hematocrit levels detected by copper sulfate screening were selected randomly to receive either 75 mg of iron per day, as ferrous gluconate, or a calcium phosphate placebo. Their ferritin, serum iron, total iron-binding capacity, zinc protoporphyrin, and hemoglobin values, as well as their...

journal_title：Transfusion

authors： Cable RG,Morse EE,Keltonic J,Kakaiya R,Kiraly T

更新日期：1988-09-01 00:00:00

abstract：:The anti-A response in a group B patient accidentally given 1 unit transfusion of A1 blood is described. The antibody response is characterized both with conventional agglutination techniques and with radioimmunoassay using pure group A antigens with different core saccharide structures (type 1, 2, and 4 chains) and c...

journal_title：Transfusion

authors： Rydberg L,Breimer ME,Samuelsson BE

更新日期：1988-09-01 00:00:00

abstract：:Sera from three unrelated persons whose red cells (RBC) had the common Scianna phenotype (Sc:1,-2) contained IgG alloantibodies directed against high-frequency RBC antigens. In each case, sera or eluates or both failed to react only with Scianna null (Sc:-1,-2) cells, although an eluate from one person was compatible ...

journal_title：Transfusion

authors： Devine P,Dawson FE,Motschman TL,Skradski KJ,Orsini L,Moulds JJ,Taswell HF

更新日期：1988-07-01 00:00:00

abstract：:Electrocardiographic (ECG) monitoring was performed on 291 donors during apheresis. Twenty-one donors (7.2%) had clinical symptoms such as discomfort, nausea, chill, numbness, and paresthesia, and 13 of this group exhibited ECG abnormalities, such as tachycardia, bradycardia, and other abnormal wave patterns. The dono...

journal_title：Transfusion

authors： Komatsu F,Shikata M

更新日期：1988-07-01 00:00:00

abstract：:Controversy exists about the suitability of blood from autologous donors for homologous use. We compared the infectious disease test results of 426 autologous donors, designated by donor history as suitable for homologous use, to those of 86,138 volunteer donations collected over the same 5 month period. Although dono...

journal_title：Transfusion

authors： Grossman BJ,Stewart NC,Grindon AJ

更新日期：1988-05-01 00:00:00

abstract：:EDTA is added to some commercial A and B cells as a means of preventing hemolysis in serum testing. Unexpected results in serum testing have been reported with EDTA-dependent agglutinins, but not with agglutinins inhibited by EDTA. A serum sample was found to contain an anti-A1 undetected by serum testing, but resulti...

journal_title：Transfusion

authors： Tedrow HE,Zeigler ZR

更新日期：1988-03-01 00:00:00

abstract：:The authors describe a method for freezing large amounts of peripheral blood lymphocytes (PBL) in a 20 percent glycerol solution. Between 0.6 and 4.3 X 10(9) cells in autologous plasma were frozen in polyethylene freezing bags in a final volume of 50 ml. The recovery after thawing averaged 89 +/- 14 percent with a mea...

journal_title：Transfusion

authors： Areman EM,Simonis TB,Carter CS,Read EJ,Klein HG

更新日期：1988-03-01 00:00:00

abstract：:The authors describe a prototype elution method employing chloroquine, a quinoline derivative, to elute IgG antibodies from the platelet surface. This chloroquine elution technique is relatively easy to perform and is effective in the removal of alloantibodies from the platelet surface. Eluted alloantibody was immunol...

journal_title：Transfusion

authors： Masel DS,Blumberg N,Heal JM

更新日期：1988-03-01 00:00:00

abstract：:Monitoring of platelet counts 1 hour after transfusion has become standard practice in most centers. In this study, platelet counts obtained 10 and 60 minutes after 48 platelet transfusions were compared. There was a close, linear relationship (r = 0.98) between these values over a wide range of posttransfusion counts...

journal_title：Transfusion

authors： O'Connell B,Lee EJ,Schiffer CA

更新日期：1988-01-01 00:00:00

abstract：:Red cells from patients with sickle cell disease (HbSS and HbSC) are more resistant to lysis in hypotonic NaCl solutions than normal (HbAA) red cells. Taking advantage of this inherent resistance to osmotic stress, patient red cells (HbSS or HbSC) were rapidly isolated from donor red cells (HbAA or HbAS) by washing wi...

journal_title：Transfusion

authors： Brown DJ

更新日期：1988-01-01 00:00:00